| 存储条件 |
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| Product Name | Glutamate receptor 1 [SD2010] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLUR 1 antibody GLUR A antibody AMPA 1 antibody AMPA selective glutamate receptor 1 antibody AMPA-selective glutamate receptor 1 antibody GluA1 antibody GLUH1 antibody GluR K1 antibody GluR-1 antibody GluR-A antibody GluR-K1 antibody GLUR1 antibody GLURA antibody GluRK1 antibody Glutamate receptor 1 antibody Glutamate receptor ionotropic AMPA 1 antibody Glutamate receptor ionotropic antibody Glutamate receptor, ionotropic, AMPA 1 antibody Gria1 antibody GRIA1_HUMAN antibody HBGR1 antibody MGC133252 antibody OTTHUMP00000160643 antibody OTTHUMP00000165781 antibody OTTHUMP00000224241 antibody OTTHUMP00000224242 antibody OTTHUMP00000224243 antibody |
| Product description | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | GLUR 1 antibody GLUR A antibody AMPA 1 antibody AMPA selective glutamate receptor 1 antibody AMPA-selective glutamate receptor 1 antibody GluA1 antibody GLUH1 antibody GluR K1 antibody GluR-1 antibody GluR-A antibody GluR-K1 antibody GLUR1 antibody GLURA antibody GluRK1 antibody Glutamate receptor 1 antibody Glutamate receptor ionotropic AMPA 1 antibody Glutamate receptor ionotropic antibody Glutamate receptor ionotropic AMPA 1 antibody Gria1 antibody GRIA1_HUMAN antibody HBGR1 antibody MGC133252 antibody OTTHUMP00000160643 antibody OTTHUMP00000165781 antibody OTTHUMP00000224241 antibody OTTHUMP00000224242 antibody OTTHUMP00000224243 antibody |
|---|---|
| Molecular Weight(MW) | 92 kDa |
| Cellular Localization | Cell membrane, Endoplasmic reticulum membrane, Cell junction. |
Application
Fig1: Western blot analysis of GluR1 on rat brain lysates using anti-GluR1 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GluR1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue using anti-GluR1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-GluR1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-GluR1 antibody. Counter stained with hematoxylin.| Positive Control | Rat brain tissue, rat cerebellum tissue, mouse brain tissue, mouse cerebellum tissue. |
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| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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