| 存储条件 |
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| Product Name | SCGB2A2 [E2-C80] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Mammaglobin 1 antibody Mammaglobin-1 antibody Mammaglobin-A antibody MGB1 antibody Scgb2a2 antibody Secretoglobin family 2A member 2 antibody SG2A2 antibody SG2A2_HUMAN antibody UGB2 antibody |
| Product description | Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B (also designated MGB2, lipophilin C, LPHC, UGB3 and SCGB2A2) is a reliable diagnostic marker for breast tumors. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Mammaglobin 1 antibody Mammaglobin-1 antibody Mammaglobin-A antibody MGB1 antibody Scgb2a2 antibody Secretoglobin family 2A member 2 antibody SG2A2 antibody SG2A2_HUMAN antibody UGB2 antibody |
|---|---|
| Molecular Weight(MW) | 11 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | Q13296 |
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Application
Fig1: Western blot analysis of Mammaglobin A on human Mammaglobin A recombinant protein using anti- Mammaglobin A antibody at 1/1,000 dilution.
Application
Fig2: ICC staining Mammaglobin A (green) and actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human mammary cancer tissue using anti- Mammaglobin A antibody. Counter stained with hematoxylin.
Application
Fig4: Flow cytometric analysis of SK-BR-3 cells with Mammaglobin A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).| Positive Control | Human Mammaglobin A recombinant protein, Hela, human mammary cancer tissue, SK-BR-3. |
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| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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