CD 94 antibody CD94 antibody CD94 antigen antibody Killer cell lectin like receptor subfamily D member 1 antibody Killer cell lectin-like receptor subfamily D member 1 antibody KLRD 1 antibody KLRD1 antibody KLRD1 protein antibody KLRD1_HUMAN antibody KP 43 antibody KP43 antibody Natural killer cells antigen CD94 antibody NK cell receptor antibody OTTHUMP00000238754 antibody OTTHUMP00000238755 antibody OTTHUMP00000238756 antibody OTTHUMP00000238758 antibody OTTHUMP00000239093 antibody
Product description
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor (3-4). CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αβ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
Immunogen
Recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
WBFC
WB:1:500-1:1,000 FC:1:100-1:200
Species Reactivity
Human
Concentration
2mg/ml
Target Information
Alternative Names
CD 94 antibody CD94 antibody CD94 antigen antibody Killer cell lectin like receptor subfamily D member 1 antibody Killer cell lectin-like receptor subfamily D member 1 antibody KLRD 1 antibody KLRD1 antibody KLRD1 protein antibody KLRD1_HUMAN antibody KP 43 antibody KP43 antibody Natural killer cells antigen CD94 antibody NK cell receptor antibody OTTHUMP00000238754 antibody OTTHUMP00000238755 antibody OTTHUMP00000238756 antibody OTTHUMP00000238758 antibody OTTHUMP00000239093 antibody
Fig1: Western blot analysis of CD94 on human CD94 recombinant protein using anti-CD94 antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of RAJI cells with CD94 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).
Positive Control
Human CD94 recombinant protein, RAJI.
Application Notes
WB:1:500-1:1,000 FC:1:100-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
