| 存储条件 |
|---|
| Product Name | FGG [C7-H9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | fggy antibody FGGY carbohydrate kinase domain containing antibody FGGY carbohydrate kinase domain-containing protein antibody FGGY_HUMAN antibody FLJ10986 antibody MGC94804 antibody OTTHUMP00000010078 antibody OTTHUMP00000010081 antibody OTTHUMP00000010082 antibody OTTHUMP00000202071 antibody RP11-242B9.1 antibody |
| Product description | The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants, which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:100-1:500 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | fggy antibody FGGY carbohydrate kinase domain containing antibody FGGY carbohydrate kinase domain-containing protein antibody FGGY_HUMAN antibody FLJ10986 antibody MGC94804 antibody OTTHUMP00000010078 antibody OTTHUMP00000010081 antibody OTTHUMP00000010082 antibody OTTHUMP00000202071 antibody RP11-242B9.1 antibody |
|---|---|
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P02679 |
|---|
Application
Fig1: Western blot analysis of FGG on human FGG recombinant protein using anti-FGG antibody at 1/1,000 dilution.
Application
Fig2: ICC staining FGG (green) and actin filaments (red) in 3T3-L1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human cerebellum tissue using anti-FGG antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-FGG antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of HepG2 cells with FGG antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human FGG recombinant protein, 3T3-L1, human cerebellum tissue, human liver cancer tissue, HepG2. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:100-1:500 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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