| 存储条件 |
|---|
| Product Name | SLC22A1 [C6-D5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | hOCT1 antibody OCT1 antibody oct1_cds antibody Organic cation transporter 1 antibody S22A1_HUMAN antibody Slc22a1 antibody solute carrier family 22 (organic cation transporter), member 1 antibody Solute carrier family 22 member 1 antibody |
| Product description | The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:1,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | hOCT1 antibody OCT1 antibody oct1_cds antibody Organic cation transporter 1 antibody S22A1_HUMAN antibody Slc22a1 antibody solute carrier family 22 (organic cation transporter) member 1 antibody Solute carrier family 22 member 1 antibody |
|---|---|
| Molecular Weight(MW) | 61 kDa |
| Cellular Localization | Basolateral cell membrane. |
| SwissProt ID | O15245 |
|---|
Application
Fig1: Western blot analysis of SLC22A1 on HEK293 (1) and SLC22A1-hIgGFc transfected HEK293 (2) cell lysate using anti-SLC22A1 antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of Jurkat cells with SLC22A1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).| Positive Control | SLC22A1-hIgGFc transfected HEK293 cell lysate, Jurkat. |
|---|---|
| Application Notes | WB:1:500-1:1,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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