| 存储条件 |
|---|
| Product Name | TWEAKR [SN20-07] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD 266 antibody CD266 antibody CD266 antigen antibody FGF inducible 14 antibody FGF-inducible 14 antibody Fibroblast growth factor inducible immediate early response protein 14 antibody Fibroblast growth factor-inducible immediate-early response protein 14 antibody FN 14 antibody FN14 antibody TNFRSF 12A antibody TNFRSF12A antibody TNR12_HUMAN antibody Tumor necrosis factor receptor superfamily member 12A antibody TWEAK R antibody Tweak receptor antibody Tweak-receptor antibody TweakR antibody |
| Product description | Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | CD 266 antibody CD266 antibody CD266 antigen antibody FGF inducible 14 antibody FGF-inducible 14 antibody Fibroblast growth factor inducible immediate early response protein 14 antibody Fibroblast growth factor-inducible immediate-early response protein 14 antibody FN 14 antibody FN14 antibody TNFRSF 12A antibody TNFRSF12A antibody TNR12_HUMAN antibody Tumor necrosis factor receptor superfamily member 12A antibody TWEAK R antibody Tweak receptor antibody Tweak-receptor antibody TweakR antibody |
|---|---|
| Molecular Weight(MW) | 14 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: Western blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: C2C12
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.| Positive Control | NIH/3T3, C2C12, mouse uterus tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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