| 存储条件 |
|---|
| Product Name | THAP11 [A4-F3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTG B43a antibody CTG B45d antibody HRIHFB2206 antibody RONIN antibody THA11_HUMAN antibody THAP 11 antibody THAP domain containing 11 antibody THAP domain-containing protein 11 antibody Thap11 antibody |
| Product description | Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification. The THAP-type zinc finger domain is suggested to have similarities with the site-specific DNA-binding domain (DBD) of Drosophila P element transposase. THAP11 (THAP domain containing 11), also known as HRIHFB2206, is a 314 amino acid protein that belongs to the THAP11 family and contains one THAP-type zinc finger. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | CTG B43a antibody CTG B45d antibody HRIHFB2206 antibody RONIN antibody THA11_HUMAN antibody THAP 11 antibody THAP domain containing 11 antibody THAP domain-containing protein 11 antibody Thap11 antibody |
|---|---|
| Molecular Weight(MW) | 45kDa,additional band 75kDa |
| Cellular Localization | Nucleus. Cytoplasm. |
| SwissProt ID | Q96EK4 |
|---|
Application
Fig1: Western blot analysis of THAP11 on Hela (1) and NTERA-2 (2) cell lysate using anti-THAP11 antibody at 1/1,000 dilution.
Application
Fig2:ICC staining THAP11 (green) and actin filaments (red) in NTERA-2 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of Hela cells with THAP11 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).| Positive Control | Hela, NTERA-2, human colon cancer tissue, human ovary cancer tissue. |
|---|---|
| Application Notes | WB:1:500 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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