| 存储条件 |
|---|
| Product Name | CD15 [D8-E10] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 3-FAL antibody Alpha-3-fucosyltransferase antibody ELAM 1 ligand antibody ELAM ligand fucosyltransferase antibody ELAM-1 ligand fucosyltransferase antibody ELFT antibody FCT3A antibody FUC-TIV antibody fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) antibody Fucosyltransferase antibody fucosyltransferase IV antibody fucT-IV antibody FUTIV antibody galactoside 3-L-fucosyltransferase antibody Leu M1 antibody Lewis X antibody LeX antibody SSEA-1 antibody stage-specific embryonic antigen 1 antibody |
| Product description | CD15, also known as Lewis X or LeX, is a carbohydrate antigen that is generated by FucT-IV (alpha 1,3-fucosyltransferase IV). Commonly found on the surface of leukocytes and some tumor cells, CD15 is a trisaccharide that is synthesized when FucT-IV transfers an α-fucose residue onto the β-GlcNAc moiety of cellular N-acetyllactosamines. CD15 functions as an adhesion molecule capable of calcium-mediated homotypic binding. Cells with high surface expression of CD15, therefore, exhibit strong self-aggregation (based on CD15-CD15 interaction) in the presence of calcium. Additionally, CD15 is thought to be a ligand for Selectins (proteins involved in mediating leukocyte-specific cellular interactions), further supporting its role as a cell-adhesion protein. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICCIHC |
| ICC:1:100-1:500 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | 3-FAL antibody Alpha-3-fucosyltransferase antibody ELAM 1 ligand antibody ELAM ligand fucosyltransferase antibody ELAM-1 ligand fucosyltransferase antibody ELFT antibody FCT3A antibody FUC-TIV antibody fucosyltransferase 4 (alpha (1 3) fucosyltransferase myeloid-specific) antibody Fucosyltransferase antibody fucosyltransferase IV antibody fucT-IV antibody FUTIV antibody galactoside 3-L-fucosyltransferase antibody Leu M1 antibody Lewis X antibody LeX antibody SSEA-1 antibody stage-specific embryonic antigen 1 antibody |
|---|---|
| Molecular Weight(MW) | 59 kDa |
| Cellular Localization | Golgi Apparatus. |
| SwissProt ID | P22083 |
|---|
Application
Fig1: ICC staining CD15 (green) and actin filaments (red) in PC-2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human cerebellum tissue using anti-CD15 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-CD15 antibody. Counter stained with hematoxylin.| Positive Control | PC-2, human cerebellum tissue, human liver cancer tissue. |
|---|---|
| Application Notes | ICC:1:100-1:500 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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