| 存储条件 |
|---|
| Product Name | POU3F2 [B8-H12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Brain 2 antibody Brain specific homeobox/POU domain protein 2 antibody Brain-2 antibodyBrain-specific homeobox/POU domain protein 2 antibody BRN 2 antibody Brn-2 antibody BRN2 antibody N Oct 3 antibody N OCT 3 Gene antibody N Oct3 antibody Nervous system specific octamer binding transcription factor antibody Nervous system-specific octamer-binding transcription factor N-Oct-3 antibody OCT 7 antibody Oct-7 antibody OCT7 antibody Octamer Binding Transcription Factor 7 antibody Octamer-binding protein 7 antibody Octamer-binding transcription factor 7 antibody OTF 7 antibody OTF-7 antibody OTF7 antibody PO3F2_HUMAN antibody POU class 3 homeobox 2, antibody POU domain class 3 transcription factor 2 antibody POU domain, class 3, transcription factor 2 antibody Pou3f2 antibody POUF 3 antibody POUF3 antibody Protein Brn 2 antibody |
| Product description | The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500-1:2,000 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | Brain 2 antibody Brain specific homeobox/POU domain protein 2 antibody Brain-2 antibodyBrain-specific homeobox/POU domain protein 2 antibody BRN 2 antibody Brn-2 antibody BRN2 antibody N Oct 3 antibody N OCT 3 Gene antibody N Oct3 antibody Nervous system specific octamer binding transcription factor antibody Nervous system-specific octamer-binding transcription factor N-Oct-3 antibody OCT 7 antibody Oct-7 antibody OCT7 antibody Octamer Binding Transcription Factor 7 antibody Octamer-binding protein 7 antibody Octamer-binding transcription factor 7 antibody OTF 7 antibody OTF-7 antibody OTF7 antibody PO3F2_HUMAN antibody POU class 3 homeobox 2 antibody POU domain class 3 transcription factor 2 antibody POU domain class 3 transcription factor 2 antibody Pou3f2 antibody POUF 3 antibody POUF3 antibody Protein Brn 2 antibody |
|---|---|
| Molecular Weight(MW) | 47 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P20265 |
|---|
Application
Fig1: Western blot analysis of POU3F2 on human POU3F2 recombinant protein using anti-POU3F2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of POU3F2 on HeLa (1) and SK-N-SH (2) cell lysate using anti-POU3F2 antibody at 1/1,000 dilution.| Positive Control | Human POU3F2 recombinant protein, SK-N-SH. |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
抱歉，暂无浏览记录
