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KCNQ1 [D3-E12]

KCNQ1 [D3-E12]

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包装规格 交货周期 质量标准 目录价 会员专享价 数量
100ul 现货2-3天 原装正品
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50ul 现货2-3天 原装正品
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基础信息
存储条件
产品详情
Product Profile
Product NameKCNQ1 [D3-E12]
Antibody TypePrimary Antibodies
Antigen AliasATFB1 antibody ATFB3 antibody FLJ26167 antibody IKs producing slow voltage-gated potassium channel subunit alpha antibody IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 antibody Jervell and Lange-Nielsen syndrome 1 antibody JLNS1 antibody KCNA8 antibody KCNA9 antibody KCNQ1 antibody KCNQ1_HUMAN antibody kidney and cardiac voltage dependend K+ channel antibody KQT-like 1 antibody Kv1.9 antibody Kv7.1 antibody KVLQT1 antibody long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1 antibody LQT antibody LQT1 antibody Potassium channel, voltage-gated, shaker-relatd subfamily, member 9 antibody Potassium voltage-gated channel subfamily KQT member 1 antibody potassium voltage-gated channel, KQT-like subfamily, member 1 antibody RWS antibody slow delayed rectifier channel subunit antibody SQT2 antibody Voltage-gated potassium channel subunit Kv7.1 antibody WRS antibody
Product descriptionThis gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
ImmunogenRecombinant protein
Key Feature
ClonalityMonoclonal
IsotypeIgG2b
Host SpeciesMouse
Tested ApplicationsWBFC

WB:1:500-1:2,000
FC:1:100-1:200
Species ReactivityHuman
Concentration2mg/ml
Target Information
Alternative NamesATFB1 antibody ATFB3 antibody FLJ26167 antibody IKs producing slow voltage-gated potassium channel subunit alpha antibody IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 antibody Jervell and Lange-Nielsen syndrome 1 antibody JLNS1 antibody KCNA8 antibody KCNA9 antibody KCNQ1 antibody KCNQ1_HUMAN antibody kidney and cardiac voltage dependend K+ channel antibody KQT-like 1 antibody Kv1.9 antibody Kv7.1 antibody KVLQT1 antibody long (electrocardiographic) QT syndrome
Ward-Romano syndrome 1 antibody LQT antibody LQT1 antibody Potassium channel
voltage-gated
shaker-relatd subfamily
member 9 antibody Potassium voltage-gated channel subfamily KQT member 1 antibody potassium voltage-gated channel
KQT-like subfamily
member 1 antibody RWS antibody slow delayed rectifier channel subunit antibody SQT2 antibody Voltage-gated potassium channel subunit Kv7.1 antibody WRS antibody
Molecular Weight(MW)75kDa (Predicted band size)
Cellular LocalizationMembrane. Cytoplasm.
Database Links
SwissProt IDP51787
Application

Application

Fig1: Western blot analysis of KCNQ1 on human KCNQ1 recombinant protein using anti-KCNQ1 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of KCNQ1 on CF-7 (1) and A431 (2) cell lysate using anti-KCNQ1 antibody at 1/1,000 dilution.

Application

Fig3:Flow cytometric analysis of MCF-7 cells with KCNQ1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive ControlHuman KCNQ1 recombinant protein, MCF-7, A431.
Application NotesWB:1:500-1:2,000
FC:1:100-1:200
Additional Information
FormLiquid
Storage InstructionsStore at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.


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