| 存储条件 |
|---|
| Product Name | BDH1 [C3-A5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) antibody 3-hydroxybutyrate dehydrogenase antibody BDH antibody BDH_HUMAN antibody BDH1 antibody D beta hydroxybutyrate dehydrogenase, mitochondrial antibody D-beta-hydroxybutyrate dehydrogenase antibody mitochondrial antibody |
| Product description | BDH1 (3-hydroxybutyrate dehydrogenase, type 1), also known as BDH or SDR9C1, is a 343 amino acid protein that localizes to the mitochondrial matrix and belongs to the short-chain dehydrogenases/reductases (SDR) family. Existing as a homotetramer, BDH1 functions to catalyze the NAD+-dependent interconversion of (R)-3-hydroxybutanoate and acetoacetate, a reaction that is allosterically activated by phosphatidylcholine. As both (R)-3-hydroxybutanoate and acetoacetate are two major ketone bodies produced during fatty acid catabolism, BDH1 plays an important role in the metabolic degradation of fatty acids. The gene encoding BDH1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | 3 hydroxybutyrate dehydrogenase (heart mitochondrial) antibody 3-hydroxybutyrate dehydrogenase antibody BDH antibody BDH_HUMAN antibody BDH1 antibody D beta hydroxybutyrate dehydrogenase mitochondrial antibody D-beta-hydroxybutyrate dehydrogenase antibody mitochondrial antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Mitochondrion matrix. |
Application
Fig1:Western blot analysis of BDH1 on HepG2 and NIH/3T3 cell lysate using anti-BDH1 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-BDH1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human colorectal cancer tissue using anti-BDH1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-BDH1 antibody. Counter stained with hematoxylin.| Positive Control | HepG2, NIH/3T3 cell lysate, human prostate tissue, human colorectal cancer tissue, human liver cancer tissue. |
|---|---|
| Application Notes | WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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