| 存储条件 |
|---|
| Product Name | KLHL21 [F4-H4] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Kelch-like protein 21 antibody KIAA0469 antibody KLH21_HUMAN antibody KLHL21 antibody MGC99635 antibody |
| Product description | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Kelch-like protein 21 antibody KIAA0469 antibody KLH21_HUMAN antibody KLHL21 antibody MGC99635 antibody |
|---|---|
| Molecular Weight(MW) | 66 kDa |
| Cellular Localization | Cytoplasm. |
| SwissProt ID | Q9UJP4 |
|---|
Application
Fig1: Western blot analysis of KLHL21 on human KLHL21 recombinant protein using anti-KLHL21 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-KLHL21 antibody. Counter stained with hematoxylin.| Positive Control | Human KLHL21 recombinant protein, human brain tissue. |
|---|---|
| Application Notes | WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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