| 存储条件 |
|---|
| Product Name | Hemoglobin subunit alpha [SN70-09] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Alpha 1 globin antibody Alpha globin antibody Alpha one globin antibody Alpha-globin antibody HBA_HUMAN antibody HBA1 antibody HBA2 antibody Hemoglobin alpha 1 antibody Hemoglobin alpha 1 chain antibody Hemoglobin alpha 1 globin chain antibody Hemoglobin alpha 2 antibody Hemoglobin alpha chain antibody Hemoglobin subunit alpha antibody MGC126895 antibody MGC126897 antibody |
| Product description | Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The α (16p13.3; 5'-ζ-pseudoz-pseudo α2-pseudo α1-α2-α1-?1-3') and β (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two α chains and two β chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between α and β chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the α1-β2 cleavage plane. When the two α1-β2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two α chains plus two β chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two α chains plus two δ chains, and fetal hemoglobin (Hb F), which consists of two α chains together with two γ chains. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:1,000 IHC:1:10-1:50 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Alpha 1 globin antibody Alpha globin antibody Alpha one globin antibody Alpha-globin antibody HBA_HUMAN antibody HBA1 antibody HBA2 antibody Hemoglobin alpha 1 antibody Hemoglobin alpha 1 chain antibody Hemoglobin alpha 1 globin chain antibody Hemoglobin alpha 2 antibody Hemoglobin alpha chain antibody Hemoglobin subunit alpha antibody MGC126895 antibody MGC126897 antibody |
|---|---|
| Molecular Weight(MW) | 15 kDa |
| Cellular Localization | Cytosol, membrane, extracellular region |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Hemoglobin subunit alpha antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Hemoglobin subunit alpha antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse embryo tissue using anti-Hemoglobin subunit alpha antibody. Counter stained with hematoxylin.| Positive Control | Human lung tissue, human spleen tissue, mouse embryo tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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