Beta glycan antibody Betaglycan antibody Betaglycan proteoglycan antibody BGCAN antibody TGBR3_HUMAN antibody TGF beta receptor type 3 antibody TGF beta receptor type III antibody TGF-beta receptor type 3 antibody TGF-beta receptor type III antibody TGFB R3 antibody TGFBR 3 antibody TGFBR3 antibody TGFR 3 antibody TGFR-3 antibody TGFR3 antibody Transforming growth factor beta receptor III antibody Transforming growth factor beta receptor III betaglycan 300kDa antibody Transforming growth factor beta receptor type 3 antibody
Product description
A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors. TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.2.
Immunogen
Recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG2b
Host Species
Mouse
Tested Applications
WB
WB:1:500-1:2,000
Species Reactivity
HumanMouse
Concentration
2mg/ml
Purification
Unpurified
Target Information
Alternative Names
Beta glycan antibody Betaglycan antibody Betaglycan proteoglycan antibody BGCAN antibody TGBR3_HUMAN antibody TGF beta receptor type 3 antibody TGF beta receptor type III antibody TGF-beta receptor type 3 antibody TGF-beta receptor type III antibody TGFB R3 antibody TGFBR 3 antibody TGFBR3 antibody TGFR 3 antibody TGFR-3 antibody TGFR3 antibody Transforming growth factor beta receptor III antibody Transforming growth factor beta receptor III betaglycan 300kDa antibody Transforming growth factor beta receptor type 3 antibody
Fig1: Western blot analysis of TGFBR3 on human TGFBR3 recombinant protein using anti-TGFBR3 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of TGFBR3 on different cell lysate using anti-TGFBR3 antibody at 1/1,000 dilution. Positive control：Line1:JurkatLine2:HeLaLine3:MCF-7Line4:F9Line5:SK-N-SHLine6:NIH3T3
