| 存储条件 |
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| Product Name | Phospho-PKC zeta(T560) [SN0753] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 14-3-3-zetaisoform antibody AI098070 antibody aPKCzeta antibody C80388 antibody EC 2.7.11.13 antibody KPCZ_HUMAN antibody nPKC zeta antibody nPKC-zeta antibody OTTHUMP00000001368 antibody OTTHUMP00000044160 antibody PKC 2 antibody PKC ZETA antibody PKC2 antibody Pkcz antibody PKCZETA antibody PKM-zeta, included antibody PRKCZ antibody Protein kinase C zeta antibody Protein kinase C zeta form antibody Protein kinase C zeta type antibody r14-3-3 antibody R74924 antibody zetaPKC antibody |
| Product description | Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (α, βI, βII, γ, δ, ε, Ω, h, θ, λ/ι, ? and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca++. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities. |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Thr560 of human PKC zeta. |
| Modification | p-T560 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 14-3-3-zetaisoform antibody AI098070 antibody aPKCzeta antibody C80388 antibody EC 2.7.11.13 antibody KPCZ_HUMAN antibody nPKC zeta antibody nPKC-zeta antibody OTTHUMP00000001368 antibody OTTHUMP00000044160 antibody PKC 2 antibody PKC ZETA antibody PKC2 antibody Pkcz antibody PKCZETA antibody PKM-zeta included antibody PRKCZ antibody Protein kinase C zeta antibody Protein kinase C zeta form antibody Protein kinase C zeta type antibody r14-3-3 antibody R74924 antibody zetaPKC antibody |
|---|---|
| Molecular Weight(MW) | 68 kDa |
| Cellular Localization | Cytoplasm, Endosome, Cell junction. |
Application
Fig1: Western blot analysis of Phospho-PKC zeta(T560) on mouse eyeball lysates using anti-Phospho-PKC zeta(T560) antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Phospho-PKC zeta(T560) antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Phospho-PKC zeta(T560) antibody. Counter stained with hematoxylin.| Positive Control | Human breast carcinoma tissue, mouse brain tissue, mouse eyeball. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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