| 存储条件 |
|---|
| Product Name | FosB [SN703] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Activator protein 1 antibody AP 1 antibody DKFZp686C0818 antibody FBJ murine osteosarcoma viral oncogene homolog B antibody fosB antibody FOSB_HUMAN antibody G0/G1 switch regulatory protein 3 antibody G0S3 antibody GOS 3 antibody GOS B antibody GOS3 antibody GOSB antibody MGC42291 antibody Oncogene FOS B antibody Oncogene FOSB antibody Protein fos B antibody Protein fosB antibody |
| Product description | The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHCIP |
| WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Activator protein 1 antibody AP 1 antibody DKFZp686C0818 antibody FBJ murine osteosarcoma viral oncogene homolog B antibody fosB antibody FOSB_HUMAN antibody G0/G1 switch regulatory protein 3 antibody G0S3 antibody GOS 3 antibody GOS B antibody GOS3 antibody GOSB antibody MGC42291 antibody Oncogene FOS B antibody Oncogene FOSB antibody Protein fos B antibody Protein fosB antibody |
|---|---|
| Molecular Weight(MW) | 48 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of FosB on human liver lysates using anti-FosB antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-FosB antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-FosB antibody. Counter stained with hematoxylin.| Positive Control | Human liver tissue, rat spleen tissue, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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