| 存储条件 |
|---|
| Product Name | FCER1A [A9-F2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Fc epsilon RI alpha antibody Fc epsilon RI alpha chain antibody Fc epsilon RI alpha-chain antibody Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody Fc fragment of IgE, high affinity I, receptor for, alpha subunit antibody Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide antibody Fc IgE receptor alpha polypeptide antibody Fc IgE receptor, alpha chain antibody Fc IgE receptor, alpha polypeptide antibody Fc of IgE high affinity I receptor for alpha polypeptide antibody Fc-epsilon RI-alpha antibody FCE 1A antibody FCE1A antibody FCER 1A antibody Fcer1a antibody FCERA_HUMAN antibody FceRI alpha antibody FcERI antibody high affinity IgE receptor antibody High affinity immunoglobulin epsilon receptor alpha subunit antibody high affinity immunoglobulin epsilon receptor alpha-subunit antibody High affinity immunoglobulin epsilon receptor subunit alpha antibody IgE Fc receptor alpha subunit antibody IgE Fc receptor subunit alpha antibody Immunoglobulin E receptor high affinity of mast cells alpha polypeptide antibody immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide antibody |
| Product description | IgE Fc Receptor I binds to the Fc region of immunoglobulin e chain with high affinity, and is responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators such as histamines, responsible for the manifestations of allergy. IgE Fc Receptor I also induces the secretion of important lymphokines, effectors of the hypersensitivity response. Receptor I is a tetramer of a heavily glycosylated α chain (Fc ε RIα), β chain and two disulfide linked γ chains. Fc ε RIα is exposed to the outer surface of the cell and contains the IgE binding site. Expression of IgE Fc RI mRNA appears to be highly specific and has been identified in mast cells and IL-3 dependent myeloid-monocyte precursor. Alternative splicing of the genomic transcript for the a chain has also been identified. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:1,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Fc epsilon RI alpha antibody Fc epsilon RI alpha chain antibody Fc epsilon RI alpha-chain antibody Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody Fc fragment of IgE high affinity I receptor for alpha subunit antibody Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody Fc IgE receptor alpha polypeptide antibody Fc IgE receptor alpha chain antibody Fc IgE receptor alpha polypeptide antibody Fc of IgE high affinity I receptor for alpha polypeptide antibody Fc-epsilon RI-alpha antibody FCE 1A antibody FCE1A antibody FCER 1A antibody Fcer1a antibody FCERA_HUMAN antibody FceRI alpha antibody FcERI antibody high affinity IgE receptor antibody High affinity immunoglobulin epsilon receptor alpha subunit antibody high affinity immunoglobulin epsilon receptor alpha-subunit antibody High affinity immunoglobulin epsilon receptor subunit alpha antibody IgE Fc receptor alpha subunit antibody IgE Fc receptor subunit alpha antibody Immunoglobulin E receptor high affinity of mast cells alpha polypeptide antibody immunoglobulin E receptor high-affinity of mast cells alpha polypeptide antibody |
|---|---|
| Cellular Localization | Cell membrane. |
| SwissProt ID | P12319 |
|---|
Application
Fig1: Western blot analysis of FCER1A on human FCER1A recombinant protein using anti-FCER1A antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of FCER1A on different cell lysate using anti-FCER1A antibody at 1/1,000 dilution. Positive control： Line1:SW620 Line2:A549 Line3:A431
Application
Fig3: Flow cytometric analysis of HEK293 cells with FCER1A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human FCER1A recombinant protein, SW620, A549, A431 cell lysate. HEK293. |
|---|---|
| Application Notes | WB:1:500-1:1,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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