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| Product Name | CD38 [SN07-20] |
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| Antibody Type | Primary Antibodies |
| Antigen Alias | Acute lymphoblastic leukemia cells antigen CD38 antibody ADP ribosyl cyclase 1 antibody ADP ribosyl cyclase antibody ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody ADP-ribosyl cyclase 1 antibody ADPRC 1 antibody ADPRC1 antibody cADPr hydrolase 1 antibody CD 38 antibody CD38 antibody CD38 antigen (p45) antibody CD38 antigen antibody CD38 molecule antibody Cd38-rs1 antibody CD38_HUMAN antibody CD38H antibody Cyclic ADP ribose hydrolase antibody Cyclic ADP ribose hydrolase 1 antibody Cyclic ADP-ribose hydrolase 1 antibody EC 3.2.2.5 antibody Ecto nicotinamide adenine dinucleotide glycohydrolase antibody I-19 antibody I19 (mouse) antibody Lymphocyte differentiation antigen CD38 antibody NAD(+) nucleosidase antibody NIM-R5 antigen antibody NIMR5 antigen (mouse) antibody OTTHUMP00000158633 antibody OTTHUMP00000217743 antibody p45 antibody T10 antibody |
| Product description | CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
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| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Acute lymphoblastic leukemia cells antigen CD38 antibody ADP ribosyl cyclase 1 antibody ADP ribosyl cyclase antibody ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody ADP-ribosyl cyclase 1 antibody ADPRC 1 antibody ADPRC1 antibody cADPr hydrolase 1 antibody CD 38 antibody CD38 antibody CD38 antigen (p45) antibody CD38 antigen antibody CD38 molecule antibody Cd38-rs1 antibody CD38_HUMAN antibody CD38H antibody Cyclic ADP ribose hydrolase antibody Cyclic ADP ribose hydrolase 1 antibody Cyclic ADP-ribose hydrolase 1 antibody EC 3.2.2.5 antibody Ecto nicotinamide adenine dinucleotide glycohydrolase antibody I-19 antibody I19 (mouse) antibody Lymphocyte differentiation antigen CD38 antibody NAD(+) nucleosidase antibody NIM-R5 antigen antibody NIMR5 antigen (mouse) antibody OTTHUMP00000158633 antibody OTTHUMP00000217743 antibody p45 antibody T10 antibody |
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| Molecular Weight(MW) | 40/50 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P28907 |
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Application
Fig1: Western blot analysis of CD38 on different lysates using anti-CD38 antibody at 1/1,000 dilution. Positive control: Lane 1: THP-1 Lane 2: Raji
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD38 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD38 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD38 antibody. Counter stained with hematoxylin.| Positive Control | THP-1, Raji, human tonsil tissue, human spleen tissue, human kidney tissue. |
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| Application Notes | WB:1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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