| 存储条件 |
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| Product Name | CD93 [E10-A10] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C1q receptor 1 antibody C1q/MBL/SPA receptor antibody C1qR antibody C1qR(p) antibody C1qr1 antibody C1QR1_HUMAN antibody C1qRp antibody CD93 antibody CD93 antigen antibody CD93 molecule antibody CDw93 antibody Complement component 1 q subcomponent receptor 1 antibody Complement component C1q receptor antibody dJ737E23.1 antibody ECSM3 antibody Matrix remodeling associated protein 4 antibody Matrix remodelling associated 4 antibody Matrix-remodeling-associated protein 4 antibody MXRA4 antibody |
| Product description | The CD93 antigen is a 652 amino acid cell-surface glycoprotein expressed by monocytes, neutrophils, platelets, microglia, and endothelial cells. CD93 was originally thought to be a putative receptor for the complement component C1q, a serum glycoprotein which plays an integral role in the activation of the classical pathway in response to immune complexes. As a result, in the literature the CD93 gene product has also been referred to as C1QR1 and C1qRp as well as MXRA4 (Matrix-remodeling-associated protein 4). Recent studies suggest that the CD93 antigen plays a role in intercellular adhesion and in clearance of apoptotic cells. CD93 is a heavily O-glycosylated, type I transmembrane protein consisting of an N-terminal domain with homology to C-type lectin domains, a tandem array of EGF-like domains, a single transmembrane domain and a short cytoplasmic tail. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | C1q receptor 1 antibody C1q/MBL/SPA receptor antibody C1qR antibody C1qR(p) antibody C1qr1 antibody C1QR1_HUMAN antibody C1qRp antibody CD93 antibody CD93 antigen antibody CD93 molecule antibody CDw93 antibody Complement component 1 q subcomponent receptor 1 antibody Complement component C1q receptor antibody dJ737E23.1 antibody ECSM3 antibody Matrix remodeling associated protein 4 antibody Matrix remodelling associated 4 antibody Matrix-remodeling-associated protein 4 antibody MXRA4 antibody |
|---|---|
| Molecular Weight(MW) | 69 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | Q9NPY3 |
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Application
Fig1: Western blot analysis of CD93 on human CD93 recombinant protein using anti-CD93 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of CD93 on HEK293 (1) and CD93-hIgGFc transfected HEK293 (2) cell lysate using anti-CD93 antibody at 1/1,000 dilution.
Application
Fig3: ICC staining CD93 (green) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-CD93 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of HepG2 cells with CD93 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human CD93 recombinant protein, CD93-hIgGFc transfected HEK293 cell lysate, human cervical cancer tissue, Hela, HepG2. |
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| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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