| 存储条件 |
|---|
| Product Name | P2RX7 [G1-D6] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATP receptor antibody P2rx7 antibody P2RX7_HUMAN antibody P2X purinoceptor 7 antibody P2X7 antibody P2Z receptor antibody Purinergic receptor antibody purinergic receptor P2X, ligand gated ion channel, 7 antibody |
| Product description | The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | ATP receptor antibody P2rx7 antibody P2RX7_HUMAN antibody P2X purinoceptor 7 antibody P2X7 antibody P2Z receptor antibody Purinergic receptor antibody purinergic receptor P2X ligand gated ion channel 7 antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | Q99572 |
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Application
Fig1: Western blot analysis of P2RX7 on human P2RX7 recombinant protein using anti-P2RX7 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of P2RX7 on HEK293 (1) and P2RX7-hIgGFc transfected HEK293 (2) cell lysate using anti-P2RX7 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of P2RX7 on different cell lysate using anti-P2RX7 antibody at 1/1,000 dilution. Positive control： Line1: A431 Line2: U251 Line3: Hela Line4: U937 Line5: HepG2
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-P2RX7 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of Hela cells with P2RX7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human P2RX7 recombinant protein, P2RX7-hIgGFc transfected HEK293 cell lysate, A431, U251, Hela, U937, HepG2 cell lysate, human esophageal cancer tissue, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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