| 存储条件 |
|---|
| Product Name | ADAMTS1 [E6-C12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody ADAM-TS 1 antibody ADAM-TS1 antibody ADAMTS 1 antibody ADAMTS antibody ADAMTS-1 antibody Adamts1 antibody ATS1_HUMAN antibody C3 C5 antibody KIAA1346, antibody METH 1 antibody METH-1 antibody |
| Product description | ADAMTS-1, also known as METH-1, C3-C5 and KIAA1346, and the related protein ADAMTS-8, also known as METH-2 and FLJ41712, represent a new family of proteins with metalloprotease, disintegrin and Thrombospondin domains. ADAMTS-1 and ADAMTS-2 are secreted and proteolytically processed proteins that are 51.7% identical but display different, non-overlapping patterns of expression in tissues and cultured celllines. Both ADAMTS proteins have been shown to be more active than Thrombospondin-1 or endostatin in preventing angiogenesis in a cornea pocket model, and both may have application for the inhibition of new blood vessel formation in a range of tumor types. The spacer region and the Thrombospondin type I motifs in the carboxy-terminus of ADAMTS-1 are important for anchoring ADAMTS-1 to the extracellular matrix. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody ADAM-TS 1 antibody ADAM-TS1 antibody ADAMTS 1 antibody ADAMTS antibody ADAMTS-1 antibody Adamts1 antibody ATS1_HUMAN antibody C3 C5 antibody KIAA1346 antibody METH 1 antibody METH-1 antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | Q9UHI8 |
|---|
Application
Fig1: Western blot analysis of ADAMTS1 on human ADAMTS1 recombinant protein using anti-ADAMTS1 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of ADAMTS1 on HEK293 (1) and ADAMTS1-hIgGFc transfected HEK293 (2) cell lysate using anti-ADAMTS1 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of ADAMTS1 on Hela cell lysate using anti-ADAMTS1 antibody at 1/1,000 dilution.
Application
Fig4: Flow cytometric analysis of Hela cells with ADAMTS1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Application
Fig5: Flow cytometric analysis of K562 cells with ADAMTS1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human ADAMTS1 recombinant protein, ADAMTS1-hIgGFc transfected HEK293 cell lysate, Hela cell lysate, Hela, K562. |
|---|---|
| Application Notes | WB:1:500 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
