| 存储条件 |
|---|
| Product Name | CBX3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CBX 3 antibody CBX3 antibody CBX3_HUMAN antibody Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody Chromobox homolog 3 antibody Chromobox protein homolog 3 antibody GAMMA antibody HECH antibody Heterochromatin like protein 1 antibody Heterochromatin protein 1 homolog gamma antibody Heterochromatin protein HP1 gamma antibody HP1 gamma antibody HP1 gamma homolog antibody HP1Hs gamma antibody Modifier 2 protein antibody |
| Product description | Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | CBX 3 antibody CBX3 antibody CBX3_HUMAN antibody Chromobox homolog 3 (HP1 gamma homolog Drosophila) antibody Chromobox homolog 3 antibody Chromobox protein homolog 3 antibody GAMMA antibody HECH antibody Heterochromatin like protein 1 antibody Heterochromatin protein 1 homolog gamma antibody Heterochromatin protein HP1 gamma antibody HP1 gamma antibody HP1 gamma homolog antibody HP1Hs gamma antibody Modifier 2 protein antibody |
|---|---|
| Molecular Weight(MW) | 21 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q13185 |
|---|
Application
Fig1: Western blot analysis of CBX3 on human CBX3 recombinant protein using anti-CBX3 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of CBX3 on HEK293 (1) and CBX3-hIgGFc transfected HEK293 (2) cell lysate using anti-CBX3 antibody at 1/1,000 dilution.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CBX3 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-CBX3 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of A431 cells with CBX3 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human CBX3 recombinant protein, CBX3-hIgGFc transfected HEK293 cell lysate, human ovarian cancer tissue, human esophageal cancer tissue, A431. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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