| 存储条件 |
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| Product Name | MOB1A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MATS 2 antibody MATS2 antibody MGC33910 antibody Mob 1A antibody Mob 1B antibody MOB 4A antibody MOB kinase activator 1B antibody Mob1 homolog 1A antibody MOB1 Mps One Binder homolog B antibody MOB1 Mps one binder kinase activator like 1A antibody Mob1A antibody Mob1B antibody MOBKL 1A antibody MOBKL1A antibody MOL1A_HUMAN antibody Mps one binder kinase activator like 1A antibody Mps one binder kinase activator-like 1A antibody Protein Mob4A antibody |
| Product description | Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. The mammalian homologs MST1 and MST2, also designated Krs-2 and Krs-1, respectively, are major regulators of cell proliferation and survival during development. MST1/MST2 phosphorylize MOBKL1A and MOBKL1B in an MST1/MST2-dependent manner in mitosis and in response to okadaic acid or H2O2. MOBKL1A and MOBKL1B, also designated MOB1A and MOB1B, bind to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1A and MOBKL1B participate in cell cycle checkpoint control and tumor inhibition. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | MATS 2 antibody MATS2 antibody MGC33910 antibody Mob 1A antibody Mob 1B antibody MOB 4A antibody MOB kinase activator 1B antibody Mob1 homolog 1A antibody MOB1 Mps One Binder homolog B antibody MOB1 Mps one binder kinase activator like 1A antibody Mob1A antibody Mob1B antibody MOBKL 1A antibody MOBKL1A antibody MOL1A_HUMAN antibody Mps one binder kinase activator like 1A antibody Mps one binder kinase activator-like 1A antibody Protein Mob4A antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| SwissProt ID | Q7L9L4 |
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Application
Fig1: Western blot analysis of MOB1A on human MOB1A recombinant protein using anti-MOB1A antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of MOB1A on HEK293 (1) and MOB1A-hIgGFc transfected HEK293 (2) cell lysate using anti-MOB1A antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with MOB1A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human MOB1A recombinant protein, MOB1A-hIgGFc transfected HEK293 cell lysate, Hela. |
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| Application Notes | WB:1:500-1:2,000 FC:1:100-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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