| 存储条件 |
|---|
| Product Name | Phospho-STAT1(S727) [SN67-04] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Signal transducer and activator of transcription 1 91kD antibody CANDF7 antibody DKFZp686B04100 antibody IMD31A antibody IMD31B antibody IMD31C antibody ISGF 3 antibody ISGF-3 antibody OTTHUMP00000163552 antibody OTTHUMP00000165046 antibody OTTHUMP00000165047 antibody OTTHUMP00000205845 antibody Signal transducer and activator of transcription 1 91kDa antibody Signal transducer and activator of transcription 1 antibody Signal transducer and activator of transcription 1, 91kD antibody Signal transducer and activator of transcription 1-alpha/beta antibody STAT 1 antibody Stat1 antibody STAT1_HUMAN antibody STAT91 antibody Transcription factor ISGF 3 components p91 p84 antibody Transcription factor ISGF-3 components p91/p84 antibody |
| Product description | Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. |
| Immunogen | recombinant protein |
| Modification | p-S727 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Signal transducer and activator of transcription 1 91kD antibody CANDF7 antibody DKFZp686B04100 antibody IMD31A antibody IMD31B antibody IMD31C antibody ISGF 3 antibody ISGF-3 antibody OTTHUMP00000163552 antibody OTTHUMP00000165046 antibody OTTHUMP00000165047 antibody OTTHUMP00000205845 antibody Signal transducer and activator of transcription 1 91kDa antibody Signal transducer and activator of transcription 1 antibody Signal transducer and activator of transcription 1 91kD antibody Signal transducer and activator of transcription 1-alpha/beta antibody STAT 1 antibody Stat1 antibody STAT1_HUMAN antibody STAT91 antibody Transcription factor ISGF 3 components p91 p84 antibody Transcription factor ISGF-3 components p91/p84 antibody |
|---|---|
| Molecular Weight(MW) | 87 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Phospho-STAT1(S727) antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Phospho-STAT1(S727) antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Phospho-STAT1(S727) antibody. Counter stained with hematoxylin.| Positive Control | Human liver cancer tissue, human breast carcinoma tissue, mouse colon tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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