| 存储条件 |
|---|
| Product Name | FNTB [SC06-44] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAAX farnesyltransferase subunit beta antibody EC 2.5.1.58 antibody EC=2.5.1.58 antibody Farnesyltransferase antibody farnesyltransferase CAAX box beta1 antibody farnesyltransferase, CAAX box, beta antibody FNTB antibody FNTB_HUMAN antibody FPTB antibody FTase beta antibody FTase-beta antibody MGC105303 antibody Protein farnesyltransferase subunit beta antibody RAS proteins prenyltransferase beta antibody Ras proteins prenyltransferase subunit beta antibody |
| Product description | Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical α and β subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The β subunit, which is known as FTβ, CAAX farnesyltransferase subunit β, or Ras proteins prenyltransferase subunit β, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The α subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IF |
| WB:1:1,000-1:2,000 ICC:1:50-1:200 | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | CAAX farnesyltransferase subunit beta antibody EC 2.5.1.58 antibody EC=2.5.1.58 antibody Farnesyltransferase antibody farnesyltransferase CAAX box beta1 antibody farnesyltransferase CAAX box beta antibody FNTB antibody FNTB_HUMAN antibody FPTB antibody FTase beta antibody FTase-beta antibody MGC105303 antibody Protein farnesyltransferase subunit beta antibody RAS proteins prenyltransferase beta antibody Ras proteins prenyltransferase subunit beta antibody |
|---|---|
| Molecular Weight(MW) | 43 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Western blot analysis of FNTB on K562 cells lysates using anti-FNTB antibody at 1/1,000 dilution.
Application
Fig2: ICC staining FNTB in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | K562, JAR. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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