| 存储条件 |
|---|
| Product Name | ROR2 [10-2D] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BDB antibody BDB1 antibody Brachydactyly type B antibody EC 2.7.10.1 antibody MGC163394 antibody Neurotrophic tyrosine kinase antibody Neurotrophic tyrosine kinase, receptor related 2 antibody NTRKR2 antibody Receptor tyrosine kinase-like orphan receptor 2 antibody receptor-related 2 antibody ROR2 antibody ROR2_HUMAN antibody Tyrosine protein kinase transmembrane receptor ROR2 antibody Tyrosine-protein kinase transmembrane receptor Ror2 antibody |
| Product description | ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt1 and Wnt3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1 or the autosomal recessive skeletal disorder, Robinow syndrome. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | BDB antibody BDB1 antibody Brachydactyly type B antibody EC 2.7.10.1 antibody MGC163394 antibody Neurotrophic tyrosine kinase antibody Neurotrophic tyrosine kinase receptor related 2 antibody NTRKR2 antibody Receptor tyrosine kinase-like orphan receptor 2 antibody receptor-related 2 antibody ROR2 antibody ROR2_HUMAN antibody Tyrosine protein kinase transmembrane receptor ROR2 antibody Tyrosine-protein kinase transmembrane receptor Ror2 antibody |
|---|---|
| Molecular Weight(MW) | 105 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | Q01974 |
|---|
Application
Fig1: Western blot analysis of ROR2 on human ROR2 recombinant protein using anti-ROR2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of ROR2 on HEK293 (1) and ROR2-hIgGFc transfected HEK293 (2) cell lysate using anti-ROR2 antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with ROR2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human ROR2 recombinant protein, ROR2-hIgGFc transfected HEK293 cell lysate, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
