DKFZp686A2068 antibody FLJ90748 antibody KRS1 antibody KRS2 antibody Mammalian STE20 like protein kinase 1 antibody Mammalian STE20 like protein kinase 2 antibody MST 1 antibody MST 2 antibody MST1 antibody MST2 antibody Serine/threonine kinase 3 (STE20 homolog yeast) antibody Serine/threonine kinase 3 (Ste20 yeast homolog) antibody Serine/threonine kinase 3 antibody Serine/threonine kinase 4 antibody Serine/threonine protein kinase 3 antibody Serine/threonine protein kinase 4 antibody Serine/threonine protein kinase Krs 1 antibody Serine/threonine protein kinase Krs 2 antibody STE20 like kinase MST1 antibody STE20 like kinase MST2 antibody STK 3 antibody STK 4 antibody STK3 antibody STK4 antibody YSK3 antibody
Product description
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIHCIP
WB:1:1,000-1:5,000 IHC:1:50-1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
DKFZp686A2068 antibody FLJ90748 antibody KRS1 antibody KRS2 antibody Mammalian STE20 like protein kinase 1 antibody Mammalian STE20 like protein kinase 2 antibody MST 1 antibody MST 2 antibody MST1 antibody MST2 antibody Serine/threonine kinase 3 (STE20 homolog yeast) antibody Serine/threonine kinase 3 (Ste20 yeast homolog) antibody Serine/threonine kinase 3 antibody Serine/threonine kinase 4 antibody Serine/threonine protein kinase 3 antibody Serine/threonine protein kinase 4 antibody Serine/threonine protein kinase Krs 1 antibody Serine/threonine protein kinase Krs 2 antibody STE20 like kinase MST1 antibody STE20 like kinase MST2 antibody STK 3 antibody STK 4 antibody STK3 antibody STK4 antibody YSK3 antibody
