| 存储条件 |
|---|
| Product Name | ATG4C [H7-E10] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APG4 autophagy 4 homolog C (S. cerevisiae) antibody APG4 autophagy 4 homolog C antibody APG4 C antibody APG4-C antibody APG4C antibody ATG 4C antibody ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody ATG4 autophagy related 4 homolog C antibody Atg4c antibody ATG4C_HUMAN antibody AUT (S. cerevisiae) like 1, cysteine endopeptidase antibody AUT like 1, cysteine endopeptidase (S. cerevisiae) antibody AUT like 1, cysteine endopeptidase antibody AUT like 3 cysteine endopeptidase antibody AUT-like 3 cysteine endopeptidase antibody AUTL1 antibody AUTL3 antibody Autophagin 3 antibody Autophagin-3 antibody Autophagy related 4C cysteine peptidase antibody Autophagy related cysteine endopeptidase 3 antibody Autophagy related protein 4 homolog C antibody Autophagy-related cysteine endopeptidase 3 antibody Autophagy-related protein 4 homolog C antibody Cysteine protease ATG4C antibody EC 3.4.22 antibody FLJ14867 antibody OTTHUMP00000010715 antibody |
| Product description | Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT-like 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase), APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish. Atg4C is highly expressed in skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP. Atg4C is also inhibited by N-ethylmaleimide. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500-1:2,000 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | APG4 autophagy 4 homolog C (S. cerevisiae) antibody APG4 autophagy 4 homolog C antibody APG4 C antibody APG4-C antibody APG4C antibody ATG 4C antibody ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody ATG4 autophagy related 4 homolog C antibody Atg4c antibody ATG4C_HUMAN antibody AUT (S. cerevisiae) like 1 cysteine endopeptidase antibody AUT like 1 cysteine endopeptidase (S. cerevisiae) antibody AUT like 1 cysteine endopeptidase antibody AUT like 3 cysteine endopeptidase antibody AUT-like 3 cysteine endopeptidase antibody AUTL1 antibody AUTL3 antibody Autophagin 3 antibody Autophagin-3 antibody Autophagy related 4C cysteine peptidase antibody Autophagy related cysteine endopeptidase 3 antibody Autophagy related protein 4 homolog C antibody Autophagy-related cysteine endopeptidase 3 antibody Autophagy-related protein 4 homolog C antibody Cysteine protease ATG4C antibody EC 3.4.22 antibody FLJ14867 antibody OTTHUMP00000010715 antibody |
|---|---|
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Cytoplasm |
| SwissProt ID | Q96DT6 |
|---|
Application
Fig1: Western blot analysis of ATG4C on human ATG4C recombinant protein using anti-ATG4C antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of ATG4C on HEK293 (1) and ATG4C-hIgGFc transfected HEK293 (2) cell lysate using anti-ATG4C antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of ATG4C on HEK293 (1) and MOLT4 (2) cell lysate using anti-ATG4C antibody at 1/1,000 dilution.| Positive Control | Human ATG4C recombinant protein, ATG4C-hIgGFc transfected HEK293 cell lysate, HEK293, MOLT4 cell lysates. |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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