| 存储条件 |
|---|
| Product Name | KBTBD8 [6G-8A] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AU040152 antibody FLJ57592 antibody KBTB8_HUMAN antibody Kbtbd8 antibody Kelch repeat and BTB (POZ) domain containing 8 antibody Kelch repeat and BTB domain containing protein 8 antibody Kelch repeat and BTB domain-containing protein 8 antibody KIAA1842 antibody MGC91215 antibody mKIAA1842 antibody OTTHUMP00000213470 antibody RGD1563166 antibody SSEC 51 antibody SSEC51 antibody T cell activation kelch repeat protein antibody T-cell activation Kelch repeat protein antibody TA KRP antibody TA-KRP antibody Takrp antibody |
| Product description | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | AU040152 antibody FLJ57592 antibody KBTB8_HUMAN antibody Kbtbd8 antibody Kelch repeat and BTB (POZ) domain containing 8 antibody Kelch repeat and BTB domain containing protein 8 antibody Kelch repeat and BTB domain-containing protein 8 antibody KIAA1842 antibody MGC91215 antibody mKIAA1842 antibody OTTHUMP00000213470 antibody RGD1563166 antibody SSEC 51 antibody SSEC51 antibody T cell activation kelch repeat protein antibody T-cell activation Kelch repeat protein antibody TA KRP antibody TA-KRP antibody Takrp antibody |
|---|---|
| Molecular Weight(MW) | 69 kDa |
| Cellular Localization | Cytoplasm, cytoskeleton |
| SwissProt ID | Q8NFY9 |
|---|
Application
Fig1: Western blot analysis of KBTBD8 on human KBTBD8 recombinant protein using anti-KBTBD8 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of KBTBD8 on HEK293 (1) and KBTBD8-hIgGFc transfected HEK293 (2) cell lysate using anti-KBTBD8 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of KBTBD8 on different cell lysate using anti-KBTBD8 antibody at 1/1,000 dilution. Positive control： Line1: A431 Line2: Jurkat Line3: Hela Line4: K562 Line5: Hek293
Application
Fig4: Flow cytometric analysis of A431 cells with KBTBD8 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human KBTBD8 recombinant protein, KBTBD8-hIgGFc transfected HEK293 cell lysate, A431, Jurkat, Hela, K562, Hek293. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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