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c-Kit [ST04-99]

c-Kit [ST04-99]

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包装规格 交货周期 质量标准 目录价 会员专享价 数量
50ul 现货2-3天 原装正品
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100ul 现货2-3天 原装正品
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20ul 现货2-3天 原装正品
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基础信息
存储条件
产品详情
Product Profile
Product Namec-Kit [ST04-99]
Antibody TypePrimary Antibodies
Antigen AliasC Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
Product descriptionThe c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Immunogenrecombinant protein
Key Feature
ClonalityMonoclonal
IsotypeIgG
Host SpeciesRecombinant rabbit
Tested ApplicationsWBIHC

WB:1:1,000
IHC:1:50-1:200
Species ReactivityHuman
Concentration1mg/ml
Target Information
Alternative NamesC Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
Molecular Weight(MW)110 kDa
Cellular LocalizationCell membrane, Cytoplasm.
Database Links
SwissProt IDP10721
Application

Application

Fig1: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Kit antibody. Counter stained with hematoxylin.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-c-Kit antibody. Counter stained with hematoxylin.
Positive ControlHuman breast carcinoma tissue, human spleen tissue.
Application NotesWB:1:1,000
IHC:1:50-1:200
Additional Information
FormLiquid
Storage InstructionsStore at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.


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