| 存储条件 |
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| Product Name | L-FABP [AH54-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FABP 1 antibody FABP1 antibody FABPL antibody FABPL_HUMAN antibody Fatty Acid Binding Protein 1 antibody Fatty acid binding protein 1 liver antibody Fatty Acid Binding Protein antibody Fatty acid-binding protein 1 antibody Fatty acid-binding protein antibody Fatty acid-binding protein liver antibody L FABP antibody L-FABP antibody liver antibody Liver-type fatty acid-binding protein antibody |
| Product description | Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Liver-specific FABP (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors and is required for cholesterol synthesis and metabolism. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWBICCIHC |
| WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 ELISA:1:5,000-1:10,000 | |
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | FABP 1 antibody FABP1 antibody FABPL antibody FABPL_HUMAN antibody Fatty Acid Binding Protein 1 antibody Fatty acid binding protein 1 liver antibody Fatty Acid Binding Protein antibody Fatty acid-binding protein 1 antibody Fatty acid-binding protein antibody Fatty acid-binding protein liver antibody L FABP antibody L-FABP antibody liver antibody Liver-type fatty acid-binding protein antibody |
|---|---|
| Molecular Weight(MW) | 14 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.
Application
Fig7: ICC staining L-FABP in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig8: ICC staining L-FABP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig9: ICC staining L-FABP in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | 293T, HepG2, A431, human liver cancer tissue, human liver tissue, human kidney tissue, mouse kidney tissue, human colon cancer tissue, mouse kidney tissue. |
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| Application Notes | WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 ELISA:1:5,000-1:10,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.08% Sodium Azide. |
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