| 存储条件 |
|---|
| Product Name | GPX1 [A6-C0-B9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AL033363 antibody Cellular glutathione peroxidase antibody Glutathione peroxidase 1 antibody Glutathione peroxidase antibody GPx 1 antibody GPx-1 antibody GPX1 antibody GPX1_HUMAN antibody GPXD antibody GSHPx-1 antibody GSHPX1 antibody MGC14399 antibody MGC88245 antibody |
| Product description | The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. |
| Immunogen | Recombinant protein within human Glutathione Peroxidase 1 aa 20-250. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | AL033363 antibody Cellular glutathione peroxidase antibody Glutathione peroxidase 1 antibody Glutathione peroxidase antibody GPx 1 antibody GPx-1 antibody GPX1 antibody GPX1_HUMAN antibody GPXD antibody GSHPx-1 antibody GSHPX1 antibody MGC14399 antibody MGC88245 antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa |
| Cellular Localization | Cytosol. Mitochondrion. |
| SwissProt ID | P07203 |
|---|
Application
Fig1: Western blot analysis of Glutathione Peroxidase 1 on THP-1 cell lysate using anti- Glutathione Peroxidase 1 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- Glutathione Peroxidase 1 antibody. Counter stained with hematoxylin.
Application
Fig4: Flow cytometric analysis of HepG2 cells with Glutathione Peroxidase 1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Positive Control | THP-1, human liver tissue, human kidney tissue, HepG2. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
