| 存储条件 |
|---|
| Product Name | CD20 [SY12-01] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB,IHC,IP |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 | |
| Species Reactivity | Human,Monkey |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | APY antibody ATOPY antibody B lymphocyte antigen CD20 antibody B Lymphocyte Cell Surface Antigen B1 antibody B-lymphocyte antigen CD20 antibody B-lymphocyte cell-surface antigen B1 antibody B-lymphocyte surface antigen B1 antibody B1 antibody Bp 35 antibody Bp35 antibody CD 20 antibody CD20 antibody CD20 antigen antibody CD20 receptor antibody CD20_HUMAN antibody CVID5 antibody Fc epsilon receptor I beta chain antibody Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody FCER1B antibody High affinity immunoglobulin epsilon receptor subunit beta antibody IgE Fc receptor subunit beta antibody IGEL antibody IGER antibody IGHER antibody LEU 16 antibody LEU16 antibody leukocyte surface antigen Leu 16 antibody Leukocyte surface antigen Leu-16 antibody Ly44 antibody Membrane spanning 4 domains A1 antibody Membrane spanning 4 domains subfamily A member 2 antibody Membrane-spanning 4-domains subfamily A member 1 antibody MS4A1 antibody MS4A2 antibody S7 antibody |
|---|---|
| Molecular Weight(MW) | 33 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | P11836 |
|---|
Application
Fig1: Western blot analysis of CD20 on Raji cell lysates using anti-CD20 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD20 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD20 antibody. Counter stained with hematoxylin.| Positive Control | Raji, human tonsil tissue, human spleen tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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