Multidrug resistance proteins (MRPs) are a subset of the ATP-binding cassette genes that are phase III detoxification proteins involved in transporting exogenous and endogenous compounds across cellular membranes. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. The MRPs characterized thus far are organic anion transporters. Many good substrates for these transporters are highly charged and do not penetrate the cell membrane.
Fig1: Immunofluorescence analysis of paraffin-embedded Rice tissue using anti-Putative multidrug resistance protein 1 antibody (green). The nuclear counter stain is DAPI (blue).
Positive Control
Rice.
Application Notes
IF:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
