| 存储条件 |
|---|
| Product Name | VDAC1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | N2441 antibody OMP2 antibody POR1 antibody hVDAC1 antibody MGC111064 antibody Mitochondrial Porin antibody Outer mitochondrial membrane protein porin 1 antibody Plasmalemmal porin antibody Porin 31HL antibody Porin 31HM antibody VDAC antibody VDAC-1 antibody Vdac1 antibody VDAC1_HUMAN antibody Voltage dependent anion channel 1 antibody Voltage dependent anion selective channel protein 1 antibody Voltage-dependent anion-selective channel protein 1 antibody YNL055C antibody YNL2441C antibody |
| Product description | Voltage-dependent anion-selective channel (VDAC1) (also referred to as porin, isoform 1) is a small protein, originally discovered in the outer membrane of mitochondria where it constitutes the major pore-forming protein. The porin protein VDAC1 allows to the outer-most membrane of the mitochondrion free permeability to low molecular-weight solutes. VDAC1 has been shown to co-immunoprecipitate with the anti-apoptotic protein Bcl-2 and suggested to be involved in forming the mitochondrial pore which releases cytochrome c during apoptosis. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHC |
| WB:1:500 IHC:1:200 ICC:1:200 | |
| Species Reactivity | HumanZebra Fish |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | N2441 antibody OMP2 antibody POR1 antibody hVDAC1 antibody MGC111064 antibody Mitochondrial Porin antibody Outer mitochondrial membrane protein porin 1 antibody Plasmalemmal porin antibody Porin 31HL antibody Porin 31HM antibody VDAC antibody VDAC-1 antibody Vdac1 antibody VDAC1_HUMAN antibody Voltage dependent anion channel 1 antibody Voltage dependent anion selective channel protein 1 antibody Voltage-dependent anion-selective channel protein 1 antibody YNL055C antibody YNL2441C antibody |
|---|---|
| Molecular Weight(MW) | 31 kDa |
| Cellular Localization | Mitochondrial membrane, cell membrane |
| SwissProt ID | P21796 |
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Application
Fig1: Western blot analysis on different cell lysates using anti-VDAC1 rabbit polyclonal antibodies.
Application
Fig2：Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-VDAC1 rabbit polyclonal antibody.
Application
Fig3: ICC staining VDAC1 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).| Positive Control | A431, human brain, Hela, Raji, HepG2, SW480 |
|---|---|
| Application Notes | WB:1:500 IHC:1:200 ICC:1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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